重组细胞因子

• Casticin promotes M2 macrophage polarisation and dorsal root ganglion neuronal autophagy to alleviate cold hyperalgesia in knee osteoarthritis by regulating histone-lysine N-methyltransferase (SETDB2). Br J Pharmacol. 2026 May 19. (IF 7.7)(Mouse IL-4)
• Reparative “Exosome-Ark” for Mitochondrial Transplantation to Reprogram Macrophages and Disrupt Pathogenic Crosstalk in Pulmonary Fibrosis. Materials Today Bio. Available online 4 May 2026, 103201. (IF 10.2)(Mouse IL-4, Human TGF-β1)
• IFN-γ-primed MSC extracellular vesicles attenuate rheumatoid arthritis via PD-L1-driven T-cell suppression and bone preservation. Journal of Controlled Release. Volume 395, 10 July 2026, 114985. (IF 11.5)(Mouse IFN-γ)
• ACE2 acts as a tumor suppressor in breast cancer by inhibiting progression via the TGF-β1/Smad pathway and potentiating immune checkpoint blockade. BBA - Molecular Basis of Disease, Volume 1872, Issue 5, June 2026, 168224. (IF 4.2)(Human TGF-β1)
• Microfluidic Nanocomposite Lubricating Microgels Localized Deliver Celastrol for Remodeling the Immune Microenvironment to Enhance Osteoarthritis Treatment. Research 2026;9:Article 1124. (IF 10.9)(Human IL-1β)
• Engineering selective PI3Kγ inhibitors with antitumor and immunomodulatory potentials. Acta Pharmaceutica Sinica B.2025,,ISSN 2211-3835. (IF 14.6)(Mouse IL-4, Mouse IL-13)